With Asperger's syndrome, teenager Jacob Hunt is unable to have the same kind of social life other boys his age have. However, like other kids with AS, he has homed in on one particular interest: forensic analysis. He normally shows up to crime scenes and helps solve the case, but this time he is the prime suspect. When a murder leads police to question Jacob, they interpret his AS symptoms as a sign of guilt and cast a very public spotlight on Jacob...

Detective Murdoch seeks to find and protect his newly discovered son from the Black Hand gang. Meanwhile, Brackenreid's son has sprung loose from jail and is on the run, and Crabtree finds himself in a compromised situation as he tries to save Effie from her kidnappers.